Two sample MR report
TUFM_Dendritic Cell (DC) against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 15 | 0.1641481 | 0.1122791 | 0.1675007 |
| Weighted median | 15 | 0.0517636 | 0.0104652 | 0.0000008 |
| Inverse variance weighted | 15 | 0.0451685 | 0.0080603 | 0.0000000 |
| Simple mode | 15 | 0.0519813 | 0.0151198 | 0.0039993 |
| Weighted mode | 15 | 0.0519813 | 0.0158311 | 0.0054379 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 9.925217 | 13 | 0.7000379 |
| Inverse variance weighted | 11.053950 | 14 | 0.6817926 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0463197 | 0.0435984 | 0.3073841 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002612 | 0 | TRUE | 0.1267925 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
